Abstract
In summary, it seems that in many neurologic disorders - of both genetic and toxic origin - mitochondrial disruption leads to an altered calcium metabolism and thus to cell death. This raises the possibility that various protective agents, such as antioxidants, that improve mitochondrial function efficiency, may be of benefit in high risk individuals.
| Original language | English |
|---|---|
| Pages (from-to) | 356-359 |
| Number of pages | 4 |
| Journal | Israel Medical Association Journal |
| Volume | 6 |
| Issue number | 6 |
| State | Published - Jun 2004 |
Keywords
- Calcium
- Genetic disease
- Mitochondria
- Neurotoxicity
- Oxidative stress