The burst of mitochondrial diseases: Neurons and calcium

Anna Fendyur, Igor Kaiserman, Lior Kasinetz, Rami Rahamimoff*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

In summary, it seems that in many neurologic disorders - of both genetic and toxic origin - mitochondrial disruption leads to an altered calcium metabolism and thus to cell death. This raises the possibility that various protective agents, such as antioxidants, that improve mitochondrial function efficiency, may be of benefit in high risk individuals.

Original languageAmerican English
Pages (from-to)356-359
Number of pages4
JournalIsrael Medical Association Journal
Volume6
Issue number6
StatePublished - Jun 2004

Keywords

  • Calcium
  • Genetic disease
  • Mitochondria
  • Neurotoxicity
  • Oxidative stress

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