The CCR5Δ32 allele is associated with reduced liver inflammation in hepatitis C virus infection

O. Wald; O. Pappo; Z. B. Ari; E. Azzaria; I. D. Wiess; I. Gafnovitch; H. Wald; U. Spengler; E. Galun; Amnon Peled

doi:10.1111/j.1365-2370.2004.00482.x

The CCR5Δ32 allele is associated with reduced liver inflammation in hepatitis C virus infection

O. Wald, O. Pappo, Z. B. Ari, E. Azzaria, I. D. Wiess, I. Gafnovitch, H. Wald, U. Spengler, E. Galun, Amnon Peled^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

CCR5Δ32 is a deletion mutation in the chemokine receptor CCR5. Liver inflammatory activity was found to be significantly reduced (P = 0.005) in Jewish Israeli patients infected with the hepatitis C virus (HCV) carrying the CCR5Δ32 allele. The CCR5Δ32 allele does not alter susceptibility to HCV infection; however, it may play a role in the progression and outcome of the disease.

Original language	English
Pages (from-to)	249-252
Number of pages	4
Journal	European Journal of Immunogenetics
Volume	31
Issue number	6
DOIs	https://doi.org/10.1111/j.1365-2370.2004.00482.x
State	Published - Dec 2004
Externally published	Yes

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10.1111/j.1365-2370.2004.00482.x

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title = "The CCR5Δ32 allele is associated with reduced liver inflammation in hepatitis C virus infection",

abstract = "CCR5Δ32 is a deletion mutation in the chemokine receptor CCR5. Liver inflammatory activity was found to be significantly reduced (P = 0.005) in Jewish Israeli patients infected with the hepatitis C virus (HCV) carrying the CCR5Δ32 allele. The CCR5Δ32 allele does not alter susceptibility to HCV infection; however, it may play a role in the progression and outcome of the disease.",

author = "O. Wald and O. Pappo and Ari, {Z. B.} and E. Azzaria and Wiess, {I. D.} and I. Gafnovitch and H. Wald and U. Spengler and E. Galun and Amnon Peled",

year = "2004",

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AU - Wald, O.

AU - Pappo, O.

AU - Ari, Z. B.

AU - Azzaria, E.

AU - Wiess, I. D.

AU - Gafnovitch, I.

AU - Wald, H.

AU - Spengler, U.

AU - Galun, E.

AU - Peled, Amnon

PY - 2004/12

Y1 - 2004/12

N2 - CCR5Δ32 is a deletion mutation in the chemokine receptor CCR5. Liver inflammatory activity was found to be significantly reduced (P = 0.005) in Jewish Israeli patients infected with the hepatitis C virus (HCV) carrying the CCR5Δ32 allele. The CCR5Δ32 allele does not alter susceptibility to HCV infection; however, it may play a role in the progression and outcome of the disease.

AB - CCR5Δ32 is a deletion mutation in the chemokine receptor CCR5. Liver inflammatory activity was found to be significantly reduced (P = 0.005) in Jewish Israeli patients infected with the hepatitis C virus (HCV) carrying the CCR5Δ32 allele. The CCR5Δ32 allele does not alter susceptibility to HCV infection; however, it may play a role in the progression and outcome of the disease.

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JO - European Journal of Immunogenetics

JF - European Journal of Immunogenetics

IS - 6

ER -

The CCR5Δ32 allele is associated with reduced liver inflammation in hepatitis C virus infection

Abstract

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