The cholinergic synapses

Hermona Soreq*, Adi Bar, Iddo Paldor

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Acetylcholine (ACh) is a leading regulatory neurotransmitter in the nervous system, which functions both directly and as modulator of other neurotransmitters. It is found in the central and peripheral nervous system, as well as in the autonomic system—both sympathetic and parasympathetic. In the central nervous system (CNS), ACh functions not only as a neurotransmitter, but also as a modulator of cognitive functions, including long-term and short-term memory, limbic activation, and alertness. No process in the mammalian body can commence without its participation.

Original languageEnglish
Pages (from-to)23-35
Number of pages13
JournalHandbook of Clinical Neurology
Volume211
DOIs
StatePublished - Jan 2025

Bibliographical note

Publisher Copyright:
© 2025 Elsevier B.V.

Keywords

  • Alzheimer disease
  • Cholinergic illnesses
  • Cholinergic synapse
  • Cholinergic treatment
  • Parkinson disease
  • Stroke

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