The chromatin roots of abnormal splicing in autism

Eden Engal, Mai Baker, Maayan Salton*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

2 Scopus citations


Spatiotemporal gene expression drives neurodevelopment. Therefore, abnormal expression during development results in atypical brain function. Alterations in gene expression have been described in autism spectrum disorder (ASD). Here, we focus on one aspect of gene expression, pre-mRNA splicing, specifically, the mechanism of its regulation by chromatin and how this is altered in ASD.

Original languageAmerican English
Pages (from-to)892-894
Number of pages3
JournalTrends in Genetics
Issue number9
StatePublished - Sep 2022

Bibliographical note

Publisher Copyright:
© 2022 Elsevier Ltd


  • autism spectrum disorder
  • chromatin
  • pre-mRNA splicing
  • splicing regulation


Dive into the research topics of 'The chromatin roots of abnormal splicing in autism'. Together they form a unique fingerprint.

Cite this