The circadian clock in inflammatory bowel diseases

Oren Froy; Yael Weintraub

doi:10.1016/j.molmed.2024.11.008

The circadian clock in inflammatory bowel diseases

Oren Froy^*, Yael Weintraub

^*Corresponding author for this work

Institute of Biochemistry, Food Science and Nutrition

Research output: Contribution to journal › Short survey › peer-review

Abstract

Inflammatory bowel diseases (IBDs) involve relapsing–remitting immune activation and inflammation. Both immune system activity and digestive tract function exhibit diurnal variations, regulated by the circadian clock. Disruption of this clock is linked to inflammation, suggesting that circadian regulators may play a pivotal role in the inflammatory process of IBD.

Original language	English
Journal	Trends in Molecular Medicine
DOIs	https://doi.org/10.1016/j.molmed.2024.11.008
State	Accepted/In press - 2024

Bibliographical note

Publisher Copyright:
© 2024 Elsevier Ltd

Keywords

circadian
clock
Crohn's disease
inflammation
inflammatory bowel disease
ulcerative colitis

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10.1016/j.molmed.2024.11.008

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title = "The circadian clock in inflammatory bowel diseases",

abstract = "Inflammatory bowel diseases (IBDs) involve relapsing–remitting immune activation and inflammation. Both immune system activity and digestive tract function exhibit diurnal variations, regulated by the circadian clock. Disruption of this clock is linked to inflammation, suggesting that circadian regulators may play a pivotal role in the inflammatory process of IBD.",

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author = "Oren Froy and Yael Weintraub",

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year = "2024",

doi = "10.1016/j.molmed.2024.11.008",

language = "אנגלית",

journal = "Trends in Molecular Medicine",

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AB - Inflammatory bowel diseases (IBDs) involve relapsing–remitting immune activation and inflammation. Both immune system activity and digestive tract function exhibit diurnal variations, regulated by the circadian clock. Disruption of this clock is linked to inflammation, suggesting that circadian regulators may play a pivotal role in the inflammatory process of IBD.

KW - circadian

KW - clock

KW - Crohn's disease

KW - inflammation

KW - inflammatory bowel disease

KW - ulcerative colitis

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JO - Trends in Molecular Medicine

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The circadian clock in inflammatory bowel diseases

Abstract

Bibliographical note

Keywords

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