The circadian clock in inflammatory bowel diseases

Oren Froy; Yael Weintraub

doi:10.1016/j.molmed.2024.11.008

The circadian clock in inflammatory bowel diseases

Oren Froy^*
, Yael Weintraub

^*Corresponding author for this work

Institute of Biochemistry, Food Science and Nutrition

Research output: Contribution to journal › Short survey › peer-review

1 Scopus citations

Abstract

Inflammatory bowel diseases (IBDs) involve relapsing–remitting immune activation and inflammation. Both immune system activity and digestive tract function exhibit diurnal variations, regulated by the circadian clock. Disruption of this clock is linked to inflammation, suggesting that circadian regulators may play a pivotal role in the inflammatory process of IBD.

Original language	English
Pages (from-to)	588-590
Number of pages	3
Journal	Trends in Molecular Medicine
Volume	31
Issue number	7
DOIs	https://doi.org/10.1016/j.molmed.2024.11.008
State	Published - Jul 2025

Bibliographical note

Publisher Copyright:
© 2024 Elsevier Ltd

Keywords

Crohn's disease
circadian
clock
inflammation
inflammatory bowel disease
ulcerative colitis

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10.1016/j.molmed.2024.11.008

Cite this

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title = "The circadian clock in inflammatory bowel diseases",

abstract = "Inflammatory bowel diseases (IBDs) involve relapsing–remitting immune activation and inflammation. Both immune system activity and digestive tract function exhibit diurnal variations, regulated by the circadian clock. Disruption of this clock is linked to inflammation, suggesting that circadian regulators may play a pivotal role in the inflammatory process of IBD.",

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author = "Oren Froy and Yael Weintraub",

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year = "2025",

month = jul,

doi = "10.1016/j.molmed.2024.11.008",

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AU - Weintraub, Yael

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AB - Inflammatory bowel diseases (IBDs) involve relapsing–remitting immune activation and inflammation. Both immune system activity and digestive tract function exhibit diurnal variations, regulated by the circadian clock. Disruption of this clock is linked to inflammation, suggesting that circadian regulators may play a pivotal role in the inflammatory process of IBD.

KW - Crohn's disease

KW - circadian

KW - clock

KW - inflammation

KW - inflammatory bowel disease

KW - ulcerative colitis

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JO - Trends in Molecular Medicine

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IS - 7

ER -

The circadian clock in inflammatory bowel diseases

Abstract

Bibliographical note

Keywords

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