TY - JOUR
T1 - The Cretan Aging Cohort
T2 - Cohort Description and Burden of Dementia and Mild Cognitive Impairment
AU - Zaganas, Ioannis V.
AU - Simos, Panagiotis
AU - Basta, Maria
AU - Kapetanaki, Stefania
AU - Panagiotakis, Symeon
AU - Koutentaki, Irini
AU - Fountoulakis, Nikolaos
AU - Bertsias, Antonios
AU - Duijker, George
AU - Tziraki, Chariklia
AU - Scarmeas, Nikolaos
AU - Plaitakis, Andreas
AU - Boumpas, Dimitrios
AU - Lionis, Christos
AU - Vgontzas, Alexandros N.
N1 - Publisher Copyright:
© The Author(s) 2018.
PY - 2019/2/1
Y1 - 2019/2/1
N2 - Our aim was to explore the burden of dementia in the Cretan Aging Cohort, comprised of 3140 persons aged ≥60 years (56.8% women, 5.8 ± 3.3 years formal education, 86.2% living in rural areas) who attended selected primary health-care facilities on the island of Crete, Greece. In the first study phase, a formal diagnosis of dementia had been reached in 4.0% of the participants. However, when selected 505 participants underwent thorough neuropsychiatric evaluation in the second phase of this study (344 with Mini-Mental State Examination [MMSE] <24 and 161 with MMSE ≥24), and results were extrapolated to the entire cohort, the prevalence of dementia and mild cognitive impairment was estimated at 10.8% (9.7%-11.9%) and 32.4% (30.8%-34.0%), respectively. Using both the field diagnostic data and the extrapolated data, the highest dementia prevalence (27.2%) was found in the 80- to 84-year-old group, who also showed the lowest educational level, apparently due to lack of schooling during World War II.
AB - Our aim was to explore the burden of dementia in the Cretan Aging Cohort, comprised of 3140 persons aged ≥60 years (56.8% women, 5.8 ± 3.3 years formal education, 86.2% living in rural areas) who attended selected primary health-care facilities on the island of Crete, Greece. In the first study phase, a formal diagnosis of dementia had been reached in 4.0% of the participants. However, when selected 505 participants underwent thorough neuropsychiatric evaluation in the second phase of this study (344 with Mini-Mental State Examination [MMSE] <24 and 161 with MMSE ≥24), and results were extrapolated to the entire cohort, the prevalence of dementia and mild cognitive impairment was estimated at 10.8% (9.7%-11.9%) and 32.4% (30.8%-34.0%), respectively. Using both the field diagnostic data and the extrapolated data, the highest dementia prevalence (27.2%) was found in the 80- to 84-year-old group, who also showed the lowest educational level, apparently due to lack of schooling during World War II.
KW - dementia
KW - dementia burden
KW - education and dementia
KW - mild cognitive impairment
UR - http://www.scopus.com/inward/record.url?scp=85059343290&partnerID=8YFLogxK
U2 - 10.1177/1533317518802414
DO - 10.1177/1533317518802414
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C2 - 30259758
AN - SCOPUS:85059343290
SN - 1533-3175
VL - 34
SP - 23
EP - 33
JO - American Journal of Alzheimer's Disease and other Dementias
JF - American Journal of Alzheimer's Disease and other Dementias
IS - 1
ER -