The eaeB gene of enteropathogenic Escherichia coli is necessary for signal transduction in epithelial cells

V. Foubister, I. Rosenshine, M. S. Donnenberg, B. B. Finlay*

*Corresponding author for this work

Research output: Contribution to journalComment/debate

131 Scopus citations

Abstract

An enteropathogenic Escherichia coli mutant carrying an internal deletion in the eaeB gene (UMD864) was unable to activate epithelial cell signals, including tyrosine phosphorylation, cytoskeletal rearrangements, and the release of inositol phosphates, indicating that the eaeB locus encodes a product that is involved in stimulating signals in epithelial cells.

Original languageAmerican English
Pages (from-to)3038-3040
Number of pages3
JournalInfection and Immunity
Volume62
Issue number7
StatePublished - 1994
Externally publishedYes

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