The effect of alfalfa saponins on growth and lysis of Physarum polycephalum

Y. Assa*, I. Chet, B. Gestetner, R. Govrin, Y. Birk, A. Bondi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

The prelytic events associated with the interaction of saponins with Physarum polycephalum membrane components were studied. It was found that alfalfa saponins form interaction products with membranal sterols, proteins and phospholipids. The interaction of saponins with proteins affect also certain membranal enzymic activities such as NADH oxidase and Malate dehydrogenase. It is suggested that although the interaction of the saponin with sterols is much more specific than with other membranal components, the lysis of plasmodia of P. polycephalum should be attributed to a concerted attack on the various membrane constituents. In continuation of these interactions, the changes of permeability of plasmodia membrane were expressed by increment of inorganic sodium ions and water influx, traced by lysis, while no efflux of ions was observed.

Original languageEnglish
Pages (from-to)77-81
Number of pages5
JournalArchives of Microbiology
Volume103
Issue number1
DOIs
StatePublished - Jan 1975

Keywords

  • Effect on Growth Interaction with Membrane Components
  • Physarum polycephalum Alfalfa Saponins

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