The effect of cyclic AMP on the rabbit corneal endothelial fluid pump

O. Neuwirth, S. Dikstein*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Perfusing presvollen deepithelialized rabbit cornea in vitro on its endothelial side with balanced salt solution containing physiological glucose concentration and 10-6M adenosine, we can obtain "temperature reversal" from 500-520p to less than 400μ during 7 hours. Low concentrations of adenosine improve the fluid pump supposedly by inhibiting adenylate cyclase, since c-AMP inhibits the pump.

Original languageEnglish
Pages (from-to)565-567
Number of pages3
JournalCurrent Eye Research
Volume2
Issue number8
DOIs
StatePublished - 1982

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