The effect of cyclic AMP on the rabbit corneal endothelial fluid pump

O. Neuwirth; S. Dikstein

doi:10.3109/02713688209069182

The effect of cyclic AMP on the rabbit corneal endothelial fluid pump

O. Neuwirth
, S. Dikstein^*

^*Corresponding author for this work

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Perfusing presvollen deepithelialized rabbit cornea in vitro on its endothelial side with balanced salt solution containing physiological glucose concentration and 10-⁶M adenosine, we can obtain "temperature reversal" from 500-520p to less than 400μ during 7 hours. Low concentrations of adenosine improve the fluid pump supposedly by inhibiting adenylate cyclase, since c-AMP inhibits the pump.

Original language	English
Pages (from-to)	565-567
Number of pages	3
Journal	Current Eye Research
Volume	2
Issue number	8
DOIs	https://doi.org/10.3109/02713688209069182
State	Published - 1982

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title = "The effect of cyclic AMP on the rabbit corneal endothelial fluid pump",

abstract = "Perfusing presvollen deepithelialized rabbit cornea in vitro on its endothelial side with balanced salt solution containing physiological glucose concentration and 10-6M adenosine, we can obtain {"}temperature reversal{"} from 500-520p to less than 400μ during 7 hours. Low concentrations of adenosine improve the fluid pump supposedly by inhibiting adenylate cyclase, since c-AMP inhibits the pump.",

author = "O. Neuwirth and S. Dikstein",

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AU - Dikstein, S.

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AB - Perfusing presvollen deepithelialized rabbit cornea in vitro on its endothelial side with balanced salt solution containing physiological glucose concentration and 10-6M adenosine, we can obtain "temperature reversal" from 500-520p to less than 400μ during 7 hours. Low concentrations of adenosine improve the fluid pump supposedly by inhibiting adenylate cyclase, since c-AMP inhibits the pump.

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JO - Current Eye Research

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The effect of cyclic AMP on the rabbit corneal endothelial fluid pump

Abstract

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