The effect of substituted aminoalkylaminoanthraquinones on eukaryotic cells

J. Katzhendler; G. Bar-Ad; M. Haran; K. F. Gean; Z. Tashma; I. Ringel; A. Ramu; U. Bachrach

The effect of substituted aminoalkylaminoanthraquinones on eukaryotic cells

J. Katzhendler, G. Bar-Ad, M. Haran, K. F. Gean, Z. Tashma, I. Ringel, A. Ramu, U. Bachrach

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Nine aminoalkylaminoanthraquinones were evaluated for their cytotoxic potency against normal and malignant mammalian cells. The 1,8-di-(aminopropylamino) derivative exhibited significant activity against several tumor cell systems and had some selectivity. The toxicity of this compound was also tested in growing chick embryos.

Original language	English
Pages (from-to)	289-294
Number of pages	6
Journal	Drug Design and Delivery
Volume	4
Issue number	4
State	Published - 1989
Externally published	Yes

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title = "The effect of substituted aminoalkylaminoanthraquinones on eukaryotic cells",

abstract = "Nine aminoalkylaminoanthraquinones were evaluated for their cytotoxic potency against normal and malignant mammalian cells. The 1,8-di-(aminopropylamino) derivative exhibited significant activity against several tumor cell systems and had some selectivity. The toxicity of this compound was also tested in growing chick embryos.",

author = "J. Katzhendler and G. Bar-Ad and M. Haran and Gean, {K. F.} and Z. Tashma and I. Ringel and A. Ramu and U. Bachrach",

year = "1989",

language = "אנגלית",

volume = "4",

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journal = "Drug Design and Delivery",

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T1 - The effect of substituted aminoalkylaminoanthraquinones on eukaryotic cells

AU - Katzhendler, J.

AU - Bar-Ad, G.

AU - Haran, M.

AU - Gean, K. F.

AU - Tashma, Z.

AU - Ringel, I.

AU - Ramu, A.

AU - Bachrach, U.

PY - 1989

Y1 - 1989

N2 - Nine aminoalkylaminoanthraquinones were evaluated for their cytotoxic potency against normal and malignant mammalian cells. The 1,8-di-(aminopropylamino) derivative exhibited significant activity against several tumor cell systems and had some selectivity. The toxicity of this compound was also tested in growing chick embryos.

AB - Nine aminoalkylaminoanthraquinones were evaluated for their cytotoxic potency against normal and malignant mammalian cells. The 1,8-di-(aminopropylamino) derivative exhibited significant activity against several tumor cell systems and had some selectivity. The toxicity of this compound was also tested in growing chick embryos.

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C2 - 2775448

AN - SCOPUS:0024363288

SN - 0884-2884

VL - 4

SP - 289

EP - 294

JO - Drug Design and Delivery

JF - Drug Design and Delivery

IS - 4

ER -

The effect of substituted aminoalkylaminoanthraquinones on eukaryotic cells

Abstract

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