The effect of the dental follicle volume of palatally impacted canines on the relative position of the adjacent teeth

Michael Lam, Eyal Dekel, Ludovica Nucci, Vicenzo Grassia, Julia Naoumova, Camila Pacheco-Pereira, Letizia Perillo, Stella Chaushu, Carlos Flores-Mir*

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review


    Objective: To assess if the dental follicle volume of palatally impacted canines (PICs) affects the relative root position of the adjacent lateral incisors (LIs) and first premolars (FPs). Materials and Methods: A retrospective cross-sectional study of 49 patients with unilaterally PICs with dental follicles who had CBCT imaging previously taken. Four orthodontic centers in different countries provided the sample. A mean difference of 5° between the angular measurements (mesiodistal tip, buccolingual inclination, or mesiodistal rotation) of the LI and FP adjacent to the PIC and the controls was considered clinically relevant. A value of 0.05 was set for significance level and a power of 80%. The minimum sample size was determined to be 26 patients. These patients were further assigned to an LI sample (n = 49) and an FP sample (n = 23), dependent on the direct contact of the dental follicle to that adjacent tooth. A manual segmentation technique was used to obtain the volumetric measurements of the dental follicle. Angular measurements of adjacent teeth were then compared to the contralateral nonimpacted side, which acted as the control. A multivariant regression analysis was performed using IBM SPSS software, and statistical significance was set at α = 0.05. Results: Adequate intra-rater reliability was accomplished. The multivariant regression analysis implied that there is no difference in the mean change in the tip, torque, and rotation of the LI and FP between the impacted and control sides when dental follicle volumes are considered (P = .509 for the LI sample and P = .804 for the FP sample). Limitations: CBCT imaging of dental follicle border delimitations, partial volume effect, and scattering are limitations. This is a convenience sample where the FP subsample is small. Conclusion: The dental follicle volume of the PICs does not seem to influence the relative position of the adjacent LI and FP mesiodistal tip, buccolingual inclination, and mesiodistal rotation. Early intervention could have been suggested to avoid certain malocclusion traits if significant displacements were demonstrated.

    Original languageAmerican English
    Article numbercjad071
    JournalEuropean Journal of Orthodontics
    Issue number1
    StatePublished - 1 Jan 2024

    Bibliographical note

    Publisher Copyright:
    © The Author(s) 2023.


    • CT
    • canine impaction
    • cone beam
    • dental follicle
    • tooth displacement


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