The enamelin (tuftelin) gene

D. Deutsch*, A. Palmon, L. Dafni, J. Catalano-Sherman, M. F. Young, L. W. Fisher

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

43 Scopus citations


This paper reviews the primary structure, characteristics and possible function of tuftelin/enamelin protein. It describes the distribution of tuftelin in the ameloblast cell and in the extracellular enamel matrix, employing high resolution protein-A gold immunocytochemistry. The chromosomal localization of the human tuftelin gene and its possible involvement in autosomally linked Amelogenesis Imperfecta, the most common hereditary disease of enamel, is also discussed.

Original languageAmerican English
Pages (from-to)135-143
Number of pages9
JournalInternational Journal of Developmental Biology
Issue number1
StatePublished - 1995


  • Chromosomal localization
  • Enamel
  • Gene
  • Mineralization
  • Tuftelin


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