Abstract
This paper reviews the primary structure, characteristics and possible function of tuftelin/enamelin protein. It describes the distribution of tuftelin in the ameloblast cell and in the extracellular enamel matrix, employing high resolution protein-A gold immunocytochemistry. The chromosomal localization of the human tuftelin gene and its possible involvement in autosomally linked Amelogenesis Imperfecta, the most common hereditary disease of enamel, is also discussed.
Original language | English |
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Pages (from-to) | 135-143 |
Number of pages | 9 |
Journal | International Journal of Developmental Biology |
Volume | 39 |
Issue number | 1 |
State | Published - 1995 |
Keywords
- Chromosomal localization
- Enamel
- Gene
- Mineralization
- Tuftelin