Abstract
This paper reviews the primary structure, characteristics and possible function of tuftelin/enamelin protein. It describes the distribution of tuftelin in the ameloblast cell and in the extracellular enamel matrix, employing high resolution protein-A gold immunocytochemistry. The chromosomal localization of the human tuftelin gene and its possible involvement in autosomally linked Amelogenesis Imperfecta, the most common hereditary disease of enamel, is also discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 135-143 |
| Number of pages | 9 |
| Journal | International Journal of Developmental Biology |
| Volume | 39 |
| Issue number | 1 |
| State | Published - 1995 |
Keywords
- Chromosomal localization
- Enamel
- Gene
- Mineralization
- Tuftelin
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