The evolution of vertebrate gastrulation

E. M. De Robertis, A. Fainsod, L. K. Gont, H. Steinbeisser

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74 Scopus citations


The availability of molecular markers now permits the analysis of the common elements of vertebrate gastrulation. While gastrulation appears to be very diverse in the vertebrates, by analyzing a head-organizer marker, goosecoid, and a marker common to all forming mesoderm, Brachyury, we attempt to identify homologous structures and equivalent stages in Xenopus, zebrafish, chick and mouse gastrulation. Using a tail-organizer marker, Xnot-2, we also discuss how the late stages of gastrulation lead to the formation of the postanal tail, a structure characteristic of the chordates.

Original languageAmerican English
Pages (from-to)117-124
Number of pages8
JournalJournal of Embryology and Experimental Morphology
Issue numberSUPPL.
StatePublished - 1994
Externally publishedYes


  • Brachyury
  • Gastrulation
  • Goosecoid
  • Spemann organizer
  • Tailbud
  • Xnot-2


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