The fatty acid synthetase complex of Haloanaerobium praevalens is not inhibited by salt

Aharon Oren*, Peter Gurevich

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Cell-free enzyme preparations of the obligately anaerobic halophilic eubacterium Haloanaerobium praevalens synthesize fatty acids from malonyl-CoA. The reaction is stimulated by NaCl and KCl at a concentration of 1 M, and only slightly inhibited by salt concentrations as high as 3 M. Thus, the fatty acid synthetase of H. praevalens is expected to the fully active at the high intracellular salt concentrations present, and it is the first fatty acid synthetase reported to be active in the presence of high salt concentrations.

Original languageAmerican English
Pages (from-to)287-290
Number of pages4
JournalFEMS Microbiology Letters
Volume108
Issue number3
DOIs
StatePublished - 15 Apr 1993

Bibliographical note

Funding Information:
This work was supported in part by a grant from the Ministry of Science and Culture, Land Niedersachsen.

Keywords

  • Anaerobic
  • Fatty acid synthetase
  • Haloanaerobium praevalens
  • Halophilic

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