Abstract
(Chemical Equation Presented) High five: H-abstraction reactivity by oxo iron(IV) complexes with a quintet ground state is greatly enhanced by exchange stabilization arising from the increased number of d-d exchange interactions near the transition state (see picture). It is postulated that nonheme enzymes evolved to make use of this fundamental mechanism in activation of strong C-H bonds.
Original language | English |
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Pages (from-to) | 3342-3345 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 49 |
Issue number | 19 |
DOIs | |
State | Published - 26 Apr 2010 |
Keywords
- Bioinorganic chemistry
- Density functional calculations
- Iron
- Metalloenzymes
- Oxido ligands