The genetics of chemoreception in the labella and tarsi of Aedes aegypti

Jackson T. Sparks, Jonathan D. Bohbot, Joseph C. Dickens*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


The yellow-fever mosquito Aedes aegypti is a major vector of human diseases, such as dengue, yellow fever, chikungunya and West Nile viruses. Chemoreceptor organs on the labella and tarsi are involved in human host evaluation and thus serve as potential foci for the disruption of blood feeding behavior. In addition to host detection, these contact chemoreceptors mediate feeding, oviposition and conspecific recognition; however, the molecular landscape of chemoreception in these tissues remains mostly uncharacterized. Here we report the expression profile of all putative chemoreception genes in the labella and tarsi of both sexes of adult Ae. aegypti and discuss their possible roles in the physiology and behavior of this important disease vector.

Original languageAmerican English
Pages (from-to)8-16
Number of pages9
JournalInsect Biochemistry and Molecular Biology
Issue number1
StatePublished - May 2014
Externally publishedYes

Bibliographical note

Funding Information:
The authors thank Dr. Shawn E. Levy and Nripesh Prasad of the Genomics Services Lab at the Hudson-Alpha Institute for Biotechnology for RNA sequencing and data analyses. We are grateful to Drs. Richard Vogt, Department of Biological Sciences, University of South Carolina and Daniel Strickman for critical review of the manuscript. This work was supported in part by a grant to J.C.D. from the Deployed War Fighter Protection (DWFP) Research Program funded by the Department of Defense through the Armed Forces Pest Management Board (AFPMB) .


  • Aedes aegypti
  • Ionotropic receptor
  • Mosquito
  • Odorant-binding protein
  • Olfactory receptor
  • Taste


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