Abstract
The results presented in this study shed new light on the molecular mechanism responsible for the control of interleukin (IL)-3-and IL-4 mediated mast cell proliferation. By measurements of AP-1 DNA-binding activity, it was found that IL-3 induced such activity while IL-4 did not. This difference in the pattern of AP-1 DNA-binding activity induced by each lymphokine indicates the differential involvement of AP-1 in the different proliferative responses of mast cells to IL-3 and IL-4.
Original language | English |
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Pages (from-to) | 57-59 |
Number of pages | 3 |
Journal | International Archives of Allergy and Immunology |
Volume | 107 |
Issue number | 1-3 |
DOIs | |
State | Published - 1995 |
Keywords
- 4AP-1
- Interleukin
- Mast Cells