The induction of adipose conversion in 3T3-L1 cells is associated with early phosphorylation of a 60-kDa nuclear protein

Ruth Brandes*, Rivka Arad, Jacob Bar-Tana

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

The induction of adipose conversion in 3T3-L1 cells by bezafibrate has been shown to be enhanced by dibutyryl-cAMP. We here report that the induction of adipose conversion in 3T3-L1 cells, by either bezafibrate and dibutyryl cAMP, or isobutylmethyxanthine alone, is associated with a very early phosphorylation of a 60-kDa acidic protein found in the nuclear fraction.

Original languageEnglish
Pages (from-to)63-65
Number of pages3
JournalFEBS Letters
Volume285
Issue number1
DOIs
StatePublished - 8 Jul 1991

Keywords

  • Adipose conversion
  • Hypolipidemic fibrate
  • IMBX
  • Protein phosphorylation
  • cAMP

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