The induction of adipose conversion in 3T3-L1 cells is associated with early phosphorylation of a 60-kDa nuclear protein

Ruth Brandes; Rivka Arad; Jacob Bar-Tana

doi:10.1016/0014-5793(91)80725-I

The induction of adipose conversion in 3T3-L1 cells is associated with early phosphorylation of a 60-kDa nuclear protein

Ruth Brandes^*, Rivka Arad, Jacob Bar-Tana

^*Corresponding author for this work

Braun School of Public Health and Community Medicine

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

The induction of adipose conversion in 3T3-L1 cells by bezafibrate has been shown to be enhanced by dibutyryl-cAMP. We here report that the induction of adipose conversion in 3T3-L1 cells, by either bezafibrate and dibutyryl cAMP, or isobutylmethyxanthine alone, is associated with a very early phosphorylation of a 60-kDa acidic protein found in the nuclear fraction.

Original language	English
Pages (from-to)	63-65
Number of pages	3
Journal	FEBS Letters
Volume	285
Issue number	1
DOIs	https://doi.org/10.1016/0014-5793(91)80725-I
State	Published - 8 Jul 1991

Keywords

Adipose conversion
Hypolipidemic fibrate
IMBX
Protein phosphorylation
cAMP

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10.1016/0014-5793(91)80725-I

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abstract = "The induction of adipose conversion in 3T3-L1 cells by bezafibrate has been shown to be enhanced by dibutyryl-cAMP. We here report that the induction of adipose conversion in 3T3-L1 cells, by either bezafibrate and dibutyryl cAMP, or isobutylmethyxanthine alone, is associated with a very early phosphorylation of a 60-kDa acidic protein found in the nuclear fraction.",

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AU - Brandes, Ruth

AU - Arad, Rivka

AU - Bar-Tana, Jacob

PY - 1991/7/8

Y1 - 1991/7/8

N2 - The induction of adipose conversion in 3T3-L1 cells by bezafibrate has been shown to be enhanced by dibutyryl-cAMP. We here report that the induction of adipose conversion in 3T3-L1 cells, by either bezafibrate and dibutyryl cAMP, or isobutylmethyxanthine alone, is associated with a very early phosphorylation of a 60-kDa acidic protein found in the nuclear fraction.

AB - The induction of adipose conversion in 3T3-L1 cells by bezafibrate has been shown to be enhanced by dibutyryl-cAMP. We here report that the induction of adipose conversion in 3T3-L1 cells, by either bezafibrate and dibutyryl cAMP, or isobutylmethyxanthine alone, is associated with a very early phosphorylation of a 60-kDa acidic protein found in the nuclear fraction.

KW - Adipose conversion

KW - Hypolipidemic fibrate

KW - IMBX

KW - Protein phosphorylation

KW - cAMP

UR - https://www.scopus.com/pages/publications/0025760651

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AN - SCOPUS:0025760651

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JO - FEBS Letters

JF - FEBS Letters

IS - 1

ER -

The induction of adipose conversion in 3T3-L1 cells is associated with early phosphorylation of a 60-kDa nuclear protein

Abstract

Keywords

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