The influence of analogues of i-fluoro-2,4-dinitrobenzene on the kinetics of irreversible inhibition of sugar transport in the human erythrocyte

E. R.A. Shimmin*, W. D. Stein

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

1. 1. The effect of analogues of 1-fluoro-2,4-dinitrobenzene on the kinetics of inhibition of the human erythrocyte transport system has been investigated. 2. 2. The analogues increase the rate of inhibition of glucose transport and modify the kinetics to a pseudo-unimolecular form in the presence of inhibitor. 3. 3. A mechanism for inhibition of the transport system by 1-fluoro-2,4-dinitrobenzene is proposed.

Original languageEnglish
Pages (from-to)308-312
Number of pages5
JournalBiochimica et Biophysica Acta - Biomembranes
Volume211
Issue number2
DOIs
StatePublished - 7 Aug 1970
Externally publishedYes

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