The influence of polyelectrolytes on the formation and phase transformation of amorphous calcium phosphate

H. Füredi-Milhofer*, P. Bar-Yosef, R. Govrin-Lippman, N. Garti

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review

2 Scopus citations

Abstract

The formation of amorphous calcium phosphate (ACP) and its transformation into octacalcium phosphate (OCP) in the presence of poly-1-glutamic acid (PGA, Mw 3 000 D and 50 000 D), poly-l-lysine (PLL, Mw 50 000 D) and polystyrene sulfonate (PSS, MW 70 000 D) has been investigated. All polyelectrolytes at low concentrations induced and at high concentrations retarded nucleation of the crystalline precipitate. In addition, the polyelectrolytes inhibited aggregation of ACP particles and growth of the crystalline phase. The intensity of the effects depended on the charge, molecular mass, and concentration of the specific polymer.

Original languageEnglish
Pages (from-to)453-456
Number of pages4
JournalKey Engineering Materials
Volume240-242
StatePublished - 2003
EventProceedings of the 15th International Symposium on Ceramics in Medicine; The Annual Meeting of the International Society for Ceramics in Medicine - Sydney, NSW, Australia
Duration: 4 Dec 20028 Dec 2002

Keywords

  • Aggregation
  • Amorphous calcium phosphate
  • Octacalcium phosphate
  • Phase transformation
  • Poly-1-lysine
  • Poly-l-glutamic acid
  • Polystyrene sulfonate
  • Precipitation

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