The influence of splenic tissue implantation upon platelet population in rabbits after splenectomy

N. Smidt, N. Laufer, N. B. .Grover, H. R. Freund, I. Charuzi

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

An investigation of the behavior of the blood platelet population following splenectomy and autologous splenic tissue implantation has been done on the rabbit. A bimodal rise in platelet size and count is observed in the postoperative period. After splenectomy, a 722 per cent increase in the platelet count and a 21.9 per cent rise in the platelet size are found. These increases are abolished by the implantation of splenic tissue. The existence of a splenic humoral factor that controls platelet production in the bone marrow is possible.

Original languageEnglish
Pages (from-to)717-720
Number of pages4
JournalSurgery Gynecology and Obstetrics
Volume153
Issue number5
StatePublished - 1981
Externally publishedYes

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