The inhibition of IGF-1 signaling promotes proteostasis by enhancing protein aggregation and deposition

Keyphrases

• Protein Homeostasis 100%
• Protein Aggregation 100%
• Protein Deposition 100%
• IGF Signaling 100%
• Signal Transduction Inhibitors 60%
• Mammalian Cells 40%
• Insulin 40%
• Aging 20%
• Neurodegeneration 20%
• High Efficiency 20%
• Alzheimer's Disease 20%
• Neurodegenerative Diseases 20%
• Quality Control 20%
• Cultured Cells 20%
• Proteotoxicity 20%
• Nematodes 20%
• Worm 20%
• Cell Systems 20%
• Therapeutic Potential 20%
• Autophagy 20%
• Misfolding 20%
• Aggresome 20%
• Prion Protein 20%
• Signaling Cascades 20%
• Proteasome Activity 20%
• Amyloid-β Peptide 20%
• Huntington's Disease 20%
• Toxic Protein 20%
• Polyglutamine 20%
• Molecular Chaperone 20%
• Neurodegenerative Illnesses 20%

Neuroscience

• Protein Aggregation 100%
• Neurodegeneration 50%
• Neurodegenerative Disorder 50%
• Alzheimer's Disease 50%
• Cell Culture 50%
• Aggresome 50%
• Prion Protein 50%
• Huntington's Disease 50%
• Proteasome 50%
• Chaperone 50%
• Polyglutamine 50%
• Autophagy 50%
• Amyloid Protein 50%

Biochemistry, Genetics and Molecular Biology

• Protein Homeostasis 100%
• Protein Aggregation 100%
• Mammalian Cell 66%
• Autophagy 33%
• Quality Control 33%
• Cell Culture 33%
• Proteotoxicity 33%
• Proteasome 33%
• Nematode 33%
• Aggresome 33%
• Prion Protein 33%
• Amyloid Protein 33%