The Jerusalem Perinatal Study cohort, 1964-2005: Methods and a review of the main results

Susan Harlap*, A. Michael Davies, Lisa Deutsch, Ronit Calderon-Margalit, Orly Manor, Ora Paltiel, Efrat Tiram, Rivka Yanetz, Mary C. Perrin, Mary B. Terry, Dolores Malaspina, Yechiel Friedlander

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

62 Scopus citations


The Jerusalem Perinatal Study recorded information on population-based cohorts of 92 408 live- and stillbirths in 1964-76, and their parents, with active surveillance of infant deaths and birth defects. Data on maternal conditions, obstetric complications and interventions during labour and delivery were recorded for 92% of the births. Subsets were surveyed with antenatal interviews in 1965-68 (n = 11 467), paediatric admissions to hospital (n = 17 782) and postpartum interviews in 1975-76 (n = 16 912). Data from some offspring were linked to records of a health examination at age 17. The offspring, mothers and fathers have been traced recently, their vital status assessed, and the data linked to Israel's Cancer Registry and Psychiatric Registry. This paper describes the different types of data available, their sources, and some potential biases. Characteristics of this unique population are shown. Findings from the study are reviewed and a list of references is provided. The cohorts provide a unique source of data for a wide variety of studies.

Original languageAmerican English
Pages (from-to)256-273
Number of pages18
JournalPaediatric and Perinatal Epidemiology
Issue number3
StatePublished - May 2007


  • BMI
  • Birth defects
  • Birth survey
  • Breast feeding
  • Cancer
  • Childhood hospitalisation
  • Diabetes
  • Longitudinal
  • Paternal age
  • Pre-eclampsia
  • Psychiatric disorder
  • Time trends


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