TY - JOUR
T1 - The lowdown on breakdown
T2 - Open questions in plant proteolysis
AU - Eckardt, Nancy A.
AU - Avin-Wittenberg, Tamar
AU - Bassham, Diane C.
AU - Chen, Poyu
AU - Chen, Qian
AU - Fang, Jun
AU - Genschik, Pascal
AU - Ghifari, Abi S.
AU - Guercio, Angelica M.
AU - Gibbs, Daniel J.
AU - Heese, Maren
AU - Jarvis, R. Paul
AU - Michaeli, Simon
AU - Murcha, Monika W.
AU - Mursalimov, Sergey
AU - Noir, Sandra
AU - Palayam, Malathy
AU - Peixoto, Bruno
AU - Rodriguez, Pedro L.
AU - Schaller, Andreas
AU - Schnittger, Arp
AU - Serino, Giovanna
AU - Shabek, Nitzan
AU - Stintzi, Annick
AU - Theodoulou, Frederica L.
AU - Üstün, Suayib
AU - van Wijk, Klaas J.
AU - Wei, Ning
AU - Xie, Qi
AU - Yu, Feifei
AU - Zhang, Hongtao
N1 - Publisher Copyright:
© The Author(s) 2024.
PY - 2024/9
Y1 - 2024/9
N2 - Proteolysis, including post-translational proteolytic processing as well as protein degradation and amino acid recycling, is an essential component of the growth and development of living organisms. In this article, experts in plant proteolysis pose and discuss compelling open questions in their areas of research. Topics covered include the role of proteolysis in the cell cycle, DNA damage response, mitochondrial function, the generation of N-terminal signals (degrons) that mark many proteins for degradation (N-terminal acetylation, the Arg/N-degron pathway, and the chloroplast N-degron pathway), developmental and metabolic signaling (photomorphogenesis, abscisic acid and strigolactone signaling, sugar metabolism, and postharvest regulation), plant responses to environmental signals (endoplasmic-reticulum-associated degradation, chloroplast-associated degradation, drought tolerance, and the growth-defense tradeoff), and the functional diversification of peptidases. We hope these thought-provoking discussions help to stimulate further research.
AB - Proteolysis, including post-translational proteolytic processing as well as protein degradation and amino acid recycling, is an essential component of the growth and development of living organisms. In this article, experts in plant proteolysis pose and discuss compelling open questions in their areas of research. Topics covered include the role of proteolysis in the cell cycle, DNA damage response, mitochondrial function, the generation of N-terminal signals (degrons) that mark many proteins for degradation (N-terminal acetylation, the Arg/N-degron pathway, and the chloroplast N-degron pathway), developmental and metabolic signaling (photomorphogenesis, abscisic acid and strigolactone signaling, sugar metabolism, and postharvest regulation), plant responses to environmental signals (endoplasmic-reticulum-associated degradation, chloroplast-associated degradation, drought tolerance, and the growth-defense tradeoff), and the functional diversification of peptidases. We hope these thought-provoking discussions help to stimulate further research.
UR - http://www.scopus.com/inward/record.url?scp=85203199671&partnerID=8YFLogxK
U2 - 10.1093/plcell/koae193
DO - 10.1093/plcell/koae193
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C2 - 38980154
AN - SCOPUS:85203199671
SN - 1040-4651
VL - 36
SP - 2931
EP - 2975
JO - Plant Cell
JF - Plant Cell
IS - 9
ER -