The modulation of transmitter release in motor nerve endings varies with the type of muscle fiber innervated

Aharon Lev-Tov*, Rachelle Fishman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Electrophysiological studies of synaptic transmission in mammalian muscles revealed substantial differences between neuromuscular synapses associated with fast versus slow-twitch motor units. Synapses of fast units exhibited much higher tetatic and post-tetanic potentiation of neurotransmitter release than those of slow units. On the other hand, the tetanic potentiation of slow units increased faster as a function of the frequency of activation than that of fast units. These differences suggest a possible specialization of neuromuscular synapses with the type of motor units they are associated with.

Original languageEnglish
Pages (from-to)379-382
Number of pages4
JournalBrain Research
Volume363
Issue number2
DOIs
StatePublished - 22 Jan 1986

Keywords

  • fast motor unit
  • neurotransmitter release
  • post-tetanic potentiation
  • slow motor unit
  • synaptic transmission
  • tetanic potentiation

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