The outcome of pregnancy following topiramate treatment: A study on 52 pregnancies

Asher Ornoy; Naama Zvi; Judy Arnon; Rebecka Wajnberg; Svetlana Shechtman; Orna Diav-Citrin

doi:10.1016/j.reprotox.2008.03.001

The outcome of pregnancy following topiramate treatment: A study on 52 pregnancies

Asher Ornoy^*
, Naama Zvi
, Judy Arnon
, Rebecka Wajnberg
, Svetlana Shechtman
, Orna Diav-Citrin

^*Corresponding author for this work

Institute for Medical Research Israel-Canada (IMRIC)

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

Abstract

In spite of a substantial increase in the use of topiramate at child bearing age, very little is known regarding its use in pregnancy. We describe the outcome of 52 pregnancies with 41 liveborn infants from which it seems that topiramate reduces birth weight without decreasing gestational age at delivery, but does not seem to increase the risk for structural defects. There was an increased rate of spontaneous abortions not related to the drug effects.

Original language	English
Pages (from-to)	388-389
Number of pages	2
Journal	Reproductive Toxicology
Volume	25
Issue number	3
DOIs	https://doi.org/10.1016/j.reprotox.2008.03.001
State	Published - Apr 2008

Keywords

Congenital anomalies
Pregnancy
Spontaneous abortions
Topiramate

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10.1016/j.reprotox.2008.03.001

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abstract = "In spite of a substantial increase in the use of topiramate at child bearing age, very little is known regarding its use in pregnancy. We describe the outcome of 52 pregnancies with 41 liveborn infants from which it seems that topiramate reduces birth weight without decreasing gestational age at delivery, but does not seem to increase the risk for structural defects. There was an increased rate of spontaneous abortions not related to the drug effects.",

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The outcome of pregnancy following topiramate treatment: A study on 52 pregnancies

Abstract

Keywords

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