The pharmacology of the hypotensive action of N,N-dimethyl para-methoxyphenylethylamine in rats

B. Shalita, S. Dikstein

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

N,N-dimethyl para-methoxyphenylethylamine prevents hypertension and reverses existing high blood pressure in DOCA-saline treated rats. Indometacine prevents its hypotensive effect, therefore the suggested mechanism is increase in prostaglandin(s) synthesis. The effect of the usual receptor antagonists on the hypotensive effect of the title compound can also be fitted into the framework of this hypothesis.

Original languageEnglish
Pages (from-to)53-69
Number of pages17
JournalResearch Communications in Chemical Pathology and Pharmacology
Volume32
Issue number1
StatePublished - 1981

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