The physiological and molecular effects of elevated CO2 levels

Zaher S. Azzam; Kfir Sharabi; Julia Guetta; Erin M. Bank; Yosef Gruenbaum

doi:10.4161/cc.9.8.11196

The physiological and molecular effects of elevated CO₂ levels

Zaher S. Azzam, Kfir Sharabi, Julia Guetta, Erin M. Bank, Yosef Gruenbaum

Institute of Biochemistry, Food Science and Nutrition

Research output: Contribution to journal › Review article › peer-review

20 Scopus citations

Abstract

Carbon dioxide (CO₂) is an end product of cellular respiration, a process by which organisms including all plants, animals, many fungi and some bacteria obtain energy.¹ CO₂ has several physiologic roles in respiration, pH buffering, autoregulation of the blood supply and others.² Here we review recent findings from studies in mammalian lung cells, Caenorhabditis elegans and Drosophila melanogaster that help shed light on the molecular sensing and response to hypercapnia.

Original language	English
Pages (from-to)	1528-1532
Number of pages	5
Journal	Cell Cycle
Volume	9
Issue number	8
DOIs	https://doi.org/10.4161/cc.9.8.11196
State	Published - 15 Apr 2010

Bibliographical note

Funding Information:
This work was supported by NIH grant HL085534 (Y.G.), Hedson fund for medical research Science, Manlam Office, Technion, The Israel Institute of Technology and The Rappaport Family Institute for Research in the Medical Sciences, Technion, Israel Institute of Technology, Haifa, Israel (Z.S.A.).

Keywords

Caenorhabditis elegans
Drosophila melanogaster
Hypercapnia
Innate immunity
Lung diseases
Muscle

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.4161/cc.9.8.11196

Cite this

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