The physiological and molecular effects of elevated CO2 levels

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations

Abstract

Carbon dioxide (CO2) is an end product of cellular respiration, a process by which organisms including all plants, animals, many fungi and some bacteria obtain energy.1 CO2 has several physiologic roles in respiration, pH buffering, autoregulation of the blood supply and others.2 Here we review recent findings from studies in mammalian lung cells, Caenorhabditis elegans and Drosophila melanogaster that help shed light on the molecular sensing and response to hypercapnia.

Original languageEnglish
Pages (from-to)1528-1532
Number of pages5
JournalCell Cycle
Volume9
Issue number8
DOIs
StatePublished - 15 Apr 2010

Bibliographical note

Funding Information:
This work was supported by NIH grant HL085534 (Y.G.), Hedson fund for medical research Science, Manlam Office, Technion, The Israel Institute of Technology and The Rappaport Family Institute for Research in the Medical Sciences, Technion, Israel Institute of Technology, Haifa, Israel (Z.S.A.).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Caenorhabditis elegans
  • Drosophila melanogaster
  • Hypercapnia
  • Innate immunity
  • Lung diseases
  • Muscle

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