The Promise, the Problems, and the Future of DNA Analysis in Paleopathology Studies

Mark Spigelman*, Dong Hoon Shin, Gila Kahila Bar Gal

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

5 Scopus citations
Original languageAmerican English
Title of host publicationA Companion to Paleopathology
Number of pages19
ISBN (Print)9781444334258
StatePublished - 8 Aug 2012


  • 1918 Spanish influenza RNA reconstruction, insight into pathogen origin
  • Ancient biomolecules of human/faunal remains, diseases in the past
  • Bone pathologies, abnormalities specific to a known cause
  • DNA degradation, and sample's preservation state
  • Direct sequencing of amplification using targeted genes, a better strategy
  • Diseases of the past and aDNA studies
  • Future of DNA in paleopathology research
  • Microbial, viral, genetic disorders, diseases and pathological lesions
  • Paleopathology, ancient in vivo lesions/diseases in skeletal remains
  • Study of ancient diseases, in understanding modern disease and cure

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