The regulatory role of eosinophils in viral, bacterial, and fungal infections

Pratibha Gaur; Ilan Zaffran; Tresa George; Fidan Rahimli Alekberli; Micha Ben-Zimra; Francesca Levi-Schaffer

doi:10.1093/cei/uxac038

The regulatory role of eosinophils in viral, bacterial, and fungal infections

Pratibha Gaur, Ilan Zaffran, Tresa George, Fidan Rahimli Alekberli, Micha Ben-Zimra, Francesca Levi-Schaffer^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

20 Scopus citations

Abstract

Eosinophils are innate immune cells typically associated with allergic and parasitic diseases. However, in recent years, eosinophils have also been ascribed a role in keeping homeostasis and in fighting several infectious diseases. Indeed, these cells circulate as mature cells in the blood and can be quickly recruited to the infected tissue. Moreover, eosinophils have all the necessary cellular equipment such as pattern recognition receptors (PRRs), pro-inflammatory cytokines, anti-bacterial proteins, and DNA traps to fight pathogens and promote an efficient immune response. This review summarizes some of the updated information on the role of eosinophils' direct and indirect mediated interactions with pathogens.

Original language	English
Pages (from-to)	72-82
Number of pages	11
Journal	Clinical and Experimental Immunology
Volume	209
Issue number	1
DOIs	https://doi.org/10.1093/cei/uxac038
State	Published - 22 Jul 2022

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© 2022 The Author(s). All rights reserved.

Keywords

bacteria
eosinophils
fungus
infections
virus

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10.1093/cei/uxac038

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The regulatory role of eosinophils in viral, bacterial, and fungal infections

Abstract

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Keywords

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