The role of BAL in the diagnosis of pulmonary mucormycosis

Mendel Glazer, Samir Nusair, Raphael Breuer, Joel Lafair, Yoav Sherman, Neville Berkman*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

59 Scopus citations

Abstract

Five patients with pulmonary mucormycosis diagnosed during life are described. All had underlying predisposing conditions: either posttransplant or hematologic malignancies. In all cases, the diagnosis was made using fiberoptic bronchoscopy. In three patients, BAL was diagnostic. In two of these patients, the diagnosis was made by identifying the typical hyphae of mucormycosis in the BAL fluid alone. Transbronchial biopsy was diagnostic in three patients. Treatment was based on IV antifungal chemotherapy together with surgical removal of involved lung tissue whenever feasible. The clinical outcome of these patients was dismal and was determined primarily by the underlying condition.

Original languageAmerican English
Pages (from-to)279-282
Number of pages4
JournalChest
Volume117
Issue number1
DOIs
StatePublished - 2000
Externally publishedYes

Keywords

  • BAL
  • Immunocompromised
  • Mucormycosis
  • Neutropenia

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