The role of single neurons in information processing

Christof Koch*, Idan Segev

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

405 Scopus citations

Abstract

Neurons carry out the many operations that extract meaningful information from sensory receptor arrays at the organism’s periphery and translate these into action, imagery and memory. Within today’s dominant computational paradigm, these operations, involving synapses, membrane ionic channels and changes in membrane potential, are thought of as steps in an algorithm or as computations. The role of neurons in these computations has evolved conceptually from that of a simple integrator of synaptic inputs until a threshold is reached and an output pulse is initiated, to a much more sophisticated processor with mixed analog-digital logic and highly adaptive synaptic elements.

Original languageEnglish
Pages (from-to)1171-1177
Number of pages7
JournalNature Neuroscience
Volume3
Issue number11s
DOIs
StatePublished - Nov 2000

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