The silence of the LADs: Dynamic genome-lamina interactions during ESC differentiation

Shai Melcer; Eran Meshorer

doi:10.1016/j.stem.2010.05.006

The silence of the LADs: Dynamic genome-lamina interactions during ESC differentiation

Shai Melcer, Eran Meshorer^*

^*Corresponding author for this work

Department of Genetics

Research output: Contribution to journal › Short survey › peer-review

7 Scopus citations

Abstract

In a recent issue of Molecular Cell, Peric-Hupkes et al. (2010) use DamID to map the interactions between chromatin and the nuclear lamina (NL) in differentiating embryonic stem cells. NL-mediated locking/unlocking of genomic regions during differentiation provides an additional facet of transcription regulation.

Original language	English
Pages (from-to)	495-497
Number of pages	3
Journal	Cell Stem Cell
Volume	6
Issue number	6
DOIs	https://doi.org/10.1016/j.stem.2010.05.006
State	Published - 4 Jun 2010

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abstract = "In a recent issue of Molecular Cell, Peric-Hupkes et al. (2010) use DamID to map the interactions between chromatin and the nuclear lamina (NL) in differentiating embryonic stem cells. NL-mediated locking/unlocking of genomic regions during differentiation provides an additional facet of transcription regulation.",

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AB - In a recent issue of Molecular Cell, Peric-Hupkes et al. (2010) use DamID to map the interactions between chromatin and the nuclear lamina (NL) in differentiating embryonic stem cells. NL-mediated locking/unlocking of genomic regions during differentiation provides an additional facet of transcription regulation.

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The silence of the LADs: Dynamic genome-lamina interactions during ESC differentiation

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