The susceptibility of cryptococcus neoformans to an antimycotic agent (G2) from alfalfa

Itzhack Polacheck*, Michael Naim

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Compound G2, 2-β-hydroxy-3 -β-O-(β-D-glucopyr anosyl)-Δ12-oleanene-23,28-dionic acid, isolated from alfalfa roots, demonstrated considerable activity against Cryptococcus neoformans (MIC value of 2 μg/ml). Compound G2 exhibited rapid killing of this fungus (MFC value of 4 μg/ml) suggesting that it might be a useful active agent in the treatment of cryptococcosis.

Original languageEnglish
Pages (from-to)481-486
Number of pages6
JournalInternational Journal of Medical Microbiology
Volume261
Issue number4
DOIs
StatePublished - 1986

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