The susceptibility of cryptococcus neoformans to an antimycotic agent (G2) from alfalfa

Itzhack Polacheck; Michael Naim

doi:10.1016/S0176-6724(86)80080-3

The susceptibility of cryptococcus neoformans to an antimycotic agent (G2) from alfalfa

Itzhack Polacheck^*
, Michael Naim

^*Corresponding author for this work

Institute of Biochemistry, Food Science and Nutrition

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Compound G2, 2-β-hydroxy-3 -β-O-(β-D-glucopyr anosyl)-Δ¹²-oleanene-23,28-dionic acid, isolated from alfalfa roots, demonstrated considerable activity against Cryptococcus neoformans (MIC value of 2 μg/ml). Compound G2 exhibited rapid killing of this fungus (MFC value of 4 μg/ml) suggesting that it might be a useful active agent in the treatment of cryptococcosis.

Original language	English
Pages (from-to)	481-486
Number of pages	6
Journal	International Journal of Medical Microbiology
Volume	261
Issue number	4
DOIs	https://doi.org/10.1016/S0176-6724(86)80080-3
State	Published - 1986

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10.1016/S0176-6724(86)80080-3

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title = "The susceptibility of cryptococcus neoformans to an antimycotic agent (G2) from alfalfa",

abstract = "Compound G2, 2-β-hydroxy-3 -β-O-(β-D-glucopyr anosyl)-Δ12-oleanene-23,28-dionic acid, isolated from alfalfa roots, demonstrated considerable activity against Cryptococcus neoformans (MIC value of 2 μg/ml). Compound G2 exhibited rapid killing of this fungus (MFC value of 4 μg/ml) suggesting that it might be a useful active agent in the treatment of cryptococcosis.",

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AB - Compound G2, 2-β-hydroxy-3 -β-O-(β-D-glucopyr anosyl)-Δ12-oleanene-23,28-dionic acid, isolated from alfalfa roots, demonstrated considerable activity against Cryptococcus neoformans (MIC value of 2 μg/ml). Compound G2 exhibited rapid killing of this fungus (MFC value of 4 μg/ml) suggesting that it might be a useful active agent in the treatment of cryptococcosis.

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The susceptibility of cryptococcus neoformans to an antimycotic agent (G2) from alfalfa

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