The trip adviser guide to the protein science world: A proposal to improve the awareness concerning the quality of recombinant proteins

Mario Lebendiker, Tsafi Danieli, Ario De Marco*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

In many research articles, where protein purification is required for various assays, (protein-protein interactions, activity assays, etc.), we always have access to the final results, but seldom have access to the raw data required for an accurate evaluation of the protein quality. This data is extremely important on one hand to critically evaluate the quality of the proteins used in the described research and, on the other hand, to allow other laboratories to safely use the described procedure in a reproducible manner. We herby propose to include a standardized methodology that can easily be incorporated in research papers. Moreover, this methodology can be utilized as a "quality control" ladder, where the more information given, will lead to a higher ranking of the article. This "quality control" stamp will allow researchers retrieving relevant and useful materials and methods in the field of protein research.

Original languageAmerican English
Article number585
JournalBMC Research Notes
Volume7
Issue number1
DOIs
StatePublished - 1 Sep 2014

Bibliographical note

Publisher Copyright:
© 2014 Lebendiker et al.;.

Keywords

  • Data annotation
  • Data reproducibility
  • Protein quality

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