The uniqueness of superoxide dismutase (SOD) - why cannot most copper compounds substitute sod in vivo?

Gldon Czapski; Sara Goldstein

doi:10.3109/10715768809055146

The uniqueness of superoxide dismutase (SOD) - why cannot most copper compounds substitute sod in vivo?

Gldon Czapski^*, Sara Goldstein

^*Corresponding author for this work

School of Nursing

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

It is shown that the copper zinc superoxide dismutase is unique in its ability to catalyze O₂- dismutation in vivo in contrast to other copper compounds which have this feature only in vitro. The reasons for this difference are discussed in terms of kinetic and thermodynamic parameters.

Original language	English
Pages (from-to)	225-229
Number of pages	5
Journal	Free Radical Research
Volume	4
Issue number	4
DOIs	https://doi.org/10.3109/10715768809055146
State	Published - 1988

Keywords

Copper compounds
Dismutation
SOD

Access to Document

10.3109/10715768809055146

Cite this

@article{0ddb155b345d46c984eb32925a250115,

title = "The uniqueness of superoxide dismutase (SOD) - why cannot most copper compounds substitute sod in vivo?",

abstract = "It is shown that the copper zinc superoxide dismutase is unique in its ability to catalyze O2- dismutation in vivo in contrast to other copper compounds which have this feature only in vitro. The reasons for this difference are discussed in terms of kinetic and thermodynamic parameters.",

keywords = "Copper compounds, Dismutation, SOD",

author = "Gldon Czapski and Sara Goldstein",

year = "1988",

doi = "10.3109/10715768809055146",

language = "אנגלית",

volume = "4",

pages = "225--229",

journal = "Free Radical Research",

issn = "1071-5762",