The use of monoclonal anti-CEA antibody immunohistochemistry in detecting the origin of oral cavity metastasis

D. W. Nitzan; N. Livni; Y. Marmary; N. Ben-Baruch; J. Sela; R. Catane

doi:10.1016/S0901-5027(05)80136-5

The use of monoclonal anti-CEA antibody immunohistochemistry in detecting the origin of oral cavity metastasis

D. W. Nitzan^*
, N. Livni
, Y. Marmary
, N. Ben-Baruch
, J. Sela
, R. Catane

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

A 75-year-old woman presented with a painless swelling in the right mandibular retromolar area and numbness of the left lower lip. Radiographic examination of the mandible demonstrated an osteolytic lesion of the ascending ramus. Biopsy revealed adenocarcinoma of obscure origin. Staining of the specimen with a monoclonal antibody specific to colon carcinoma revealed its origin. On subsequent examinations, a primary tumor in the rectosigmoid region with extensive lung, liver and skeletal metastases were diagnosed. This unusual case of colonorectal carcinoma, presenting as a metastatic lesion of the mandible, was readily diagnosed by a novel immunohistochemical technique that utilizes highly specific monoclonal antibodies.

Original language	English
Pages (from-to)	162-164
Number of pages	3
Journal	International Journal of Oral and Maxillofacial Surgery
Volume	19
Issue number	3
DOIs	https://doi.org/10.1016/S0901-5027(05)80136-5
State	Published - Jun 1990
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

adenocarcinoma
metastasis
monoclonal anti-CEA antibodies

Access to Document

10.1016/S0901-5027(05)80136-5

Cite this

@article{9f42539a9bb8409ea5c2292692d00527,

title = "The use of monoclonal anti-CEA antibody immunohistochemistry in detecting the origin of oral cavity metastasis",

abstract = "A 75-year-old woman presented with a painless swelling in the right mandibular retromolar area and numbness of the left lower lip. Radiographic examination of the mandible demonstrated an osteolytic lesion of the ascending ramus. Biopsy revealed adenocarcinoma of obscure origin. Staining of the specimen with a monoclonal antibody specific to colon carcinoma revealed its origin. On subsequent examinations, a primary tumor in the rectosigmoid region with extensive lung, liver and skeletal metastases were diagnosed. This unusual case of colonorectal carcinoma, presenting as a metastatic lesion of the mandible, was readily diagnosed by a novel immunohistochemical technique that utilizes highly specific monoclonal antibodies.",

keywords = "adenocarcinoma, metastasis, monoclonal anti-CEA antibodies",

author = "Nitzan, \{D. W.\} and N. Livni and Y. Marmary and N. Ben-Baruch and J. Sela and R. Catane",

year = "1990",

month = jun,

doi = "10.1016/S0901-5027(05)80136-5",

language = "אנגלית",

volume = "19",

pages = "162--164",

journal = "International Journal of Oral and Maxillofacial Surgery",

issn = "0901-5027",

publisher = "Churchill Livingstone",

number = "3",

}

TY - JOUR

T1 - The use of monoclonal anti-CEA antibody immunohistochemistry in detecting the origin of oral cavity metastasis

AU - Nitzan, D. W.

AU - Livni, N.

AU - Marmary, Y.

AU - Ben-Baruch, N.

AU - Sela, J.

AU - Catane, R.

PY - 1990/6

Y1 - 1990/6

N2 - A 75-year-old woman presented with a painless swelling in the right mandibular retromolar area and numbness of the left lower lip. Radiographic examination of the mandible demonstrated an osteolytic lesion of the ascending ramus. Biopsy revealed adenocarcinoma of obscure origin. Staining of the specimen with a monoclonal antibody specific to colon carcinoma revealed its origin. On subsequent examinations, a primary tumor in the rectosigmoid region with extensive lung, liver and skeletal metastases were diagnosed. This unusual case of colonorectal carcinoma, presenting as a metastatic lesion of the mandible, was readily diagnosed by a novel immunohistochemical technique that utilizes highly specific monoclonal antibodies.

AB - A 75-year-old woman presented with a painless swelling in the right mandibular retromolar area and numbness of the left lower lip. Radiographic examination of the mandible demonstrated an osteolytic lesion of the ascending ramus. Biopsy revealed adenocarcinoma of obscure origin. Staining of the specimen with a monoclonal antibody specific to colon carcinoma revealed its origin. On subsequent examinations, a primary tumor in the rectosigmoid region with extensive lung, liver and skeletal metastases were diagnosed. This unusual case of colonorectal carcinoma, presenting as a metastatic lesion of the mandible, was readily diagnosed by a novel immunohistochemical technique that utilizes highly specific monoclonal antibodies.

KW - adenocarcinoma

KW - metastasis

KW - monoclonal anti-CEA antibodies

UR - https://www.scopus.com/pages/publications/0025091399

U2 - 10.1016/S0901-5027(05)80136-5

DO - 10.1016/S0901-5027(05)80136-5

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 2114461

AN - SCOPUS:0025091399

SN - 0901-5027

VL - 19

SP - 162

EP - 164

JO - International Journal of Oral and Maxillofacial Surgery

JF - International Journal of Oral and Maxillofacial Surgery

IS - 3

ER -

The use of monoclonal anti-CEA antibody immunohistochemistry in detecting the origin of oral cavity metastasis

Abstract

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this