TY - JOUR
T1 - The use of phospholipid liposomes for lithium administration. Polydipsic effect and tissue distribution of lithium
AU - ZILBERMAN, YAEL
AU - LICHTENBERG, DOV
AU - GUTMAN, YEHUDA
PY - 1979/9
Y1 - 1979/9
N2 - Administration of lithium entrapped in phospholipid liposomes increased the lithium‐induced polydipsia, but did not accelerate the onset of this effect. It also resulted in a larger accumulation of lithium in the liver, kidney and spleen, but not in the brain. The time course of polydipsia suggests that it depends on the intracellular lithium concentration. However, the rate of development of this effect depends on some additional factor. 1979 Royal Pharmaceutical Society of Great Britain
AB - Administration of lithium entrapped in phospholipid liposomes increased the lithium‐induced polydipsia, but did not accelerate the onset of this effect. It also resulted in a larger accumulation of lithium in the liver, kidney and spleen, but not in the brain. The time course of polydipsia suggests that it depends on the intracellular lithium concentration. However, the rate of development of this effect depends on some additional factor. 1979 Royal Pharmaceutical Society of Great Britain
UR - http://www.scopus.com/inward/record.url?scp=0018648518&partnerID=8YFLogxK
U2 - 10.1111/j.2042-7158.1979.tb13604.x
DO - 10.1111/j.2042-7158.1979.tb13604.x
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C2 - 41065
AN - SCOPUS:0018648518
SN - 0022-3573
VL - 31
SP - 619
EP - 621
JO - Journal of Pharmacy and Pharmacology
JF - Journal of Pharmacy and Pharmacology
IS - 1
ER -