Three-dimensional reconstruction of cytochrome oxidase vesicle crystals prepared by cholate solubilization

Chong H. Kim, Michael Radermacher, Martin Kessel, Joachim Frank, Tsoo E. King*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Cytochrome oxidase vesicle crystals with long-range order have been obtained from cholate-solubilized, highly purified reconstitutively active preparations. These crystals, which are suitable for electron-microscopic structure investigation, show pgg symmetry in the 0° projection. Using Fourier reconstruction and modified back-projection methods, a three-dimensional reconstruction has been obtained at a resolution of 25 Å. Our structural results are in agreement with the model of Henderson . [J. Mol. Biol. 112, 631 (1977)] obtained for their Triton-derived crystals.

Original languageEnglish
Pages (from-to)163-169
Number of pages7
JournalJournal of Inorganic Biochemistry
Volume23
Issue number3-4
DOIs
StatePublished - 1985
Externally publishedYes

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