Trace element analysis of liposomal formulations by diagnostic X-ray fluorescence spectrometry (DXS)

Raphael Gorodetsky; Shimon Amselem; Yechezkel Barenholz

doi:10.1016/0009-3084(93)90055-8

Trace element analysis of liposomal formulations by diagnostic X-ray fluorescence spectrometry (DXS)

Raphael Gorodetsky
, Shimon Amselem
, Yechezkel Barenholz^*

^*Corresponding author for this work

Alexander Silberman Institute of Life Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Concentrations of Ca, Fe, Cu and Zn in liposomal doxorubicin were determined using diagnostic X-ray fluorescence spectrometry (DXS). No processing of the liposomes was required. This method was applied successfully for quality control of different liposomal formulations.

Original language	English
Pages (from-to)	31-34
Number of pages	4
Journal	Chemistry and Physics of Lipids
Volume	64
Issue number	1-3
DOIs	https://doi.org/10.1016/0009-3084(93)90055-8
State	Published - Sep 1993

Keywords

Ca
Cu
Fe
Zn
analysis
diagnostic X-ray spectroscopy (DXS)
liposomes
lipsome quality control
trace elements

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10.1016/0009-3084(93)90055-8

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title = "Trace element analysis of liposomal formulations by diagnostic X-ray fluorescence spectrometry (DXS)",

abstract = "Concentrations of Ca, Fe, Cu and Zn in liposomal doxorubicin were determined using diagnostic X-ray fluorescence spectrometry (DXS). No processing of the liposomes was required. This method was applied successfully for quality control of different liposomal formulations.",

keywords = "Ca, Cu, Fe, Zn, analysis, diagnostic X-ray spectroscopy (DXS), liposomes, lipsome quality control, trace elements",

author = "Raphael Gorodetsky and Shimon Amselem and Yechezkel Barenholz",

year = "1993",

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AU - Amselem, Shimon

AU - Barenholz, Yechezkel

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N2 - Concentrations of Ca, Fe, Cu and Zn in liposomal doxorubicin were determined using diagnostic X-ray fluorescence spectrometry (DXS). No processing of the liposomes was required. This method was applied successfully for quality control of different liposomal formulations.

AB - Concentrations of Ca, Fe, Cu and Zn in liposomal doxorubicin were determined using diagnostic X-ray fluorescence spectrometry (DXS). No processing of the liposomes was required. This method was applied successfully for quality control of different liposomal formulations.

KW - Ca

KW - Cu

KW - Fe

KW - Zn

KW - analysis

KW - diagnostic X-ray spectroscopy (DXS)

KW - liposomes

KW - lipsome quality control

KW - trace elements

UR - https://www.scopus.com/pages/publications/0027527393

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AN - SCOPUS:0027527393

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JO - Chemistry and Physics of Lipids

JF - Chemistry and Physics of Lipids

IS - 1-3

ER -

Trace element analysis of liposomal formulations by diagnostic X-ray fluorescence spectrometry (DXS)

Abstract

Keywords

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