Transcription complexes recruit a chaperone to perform cotranscriptional processing of tRNA

Nayef Jarrous, Dhivakar Mani

Research output: Contribution to journalArticlepeer-review

Abstract

Leone et al.1 reveal that Pol III transcription complexes recruit a chaperone, HSP70, to execute cotranscriptional cleavage of precursor tRNA. HSP70 binds to the polymerase and translocates to nascent precursor tRNA and then tRNA. The last complex facilitates Pol III to engage in a new, efficient transcription cycle with another HSP70.

Original languageAmerican English
Pages (from-to)619-620
Number of pages2
JournalMolecular Cell
Volume84
Issue number4
DOIs
StatePublished - 15 Feb 2024

Bibliographical note

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Copyright © 2024 Elsevier Inc. All rights reserved.

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