Treating tumors with a vaccinia virus expressing IFNΒ Illustrates the complex relationships between oncolytic ability and immunogenicity

Keyphrases

• Tumor 100%
• Immunogenicity 100%
• CD8+ T Cells 100%
• Vaccinia Virus 100%
• Oncolytic 100%
• TC-1 Tumor 100%
• Tumor Killing 100%
• Lung Cancer 50%
• Recombinant 50%
• Immune System 50%
• Immune Response 50%
• Innate Immune Response 50%
• Viral Replication 50%
• Interferon-α (IFN-α) 50%
• Antitumor 50%
• Oncolytic Effect 50%
• Viral Vectors 50%
• Tumor Model 50%
• Adenovirus 50%
• In Vivo Efficacy 50%
• Syngeneic Mice 50%
• Anti-tumor Response 50%
• Antitumor Activity 50%
• Vaccinium 50%
• Oncolytic Virus 50%
• Local Inflammatory Response 50%
• Non-replicating 50%
• Murine Tumor Model 50%
• Therapeutic Vaccine 50%
• Killing Mechanism 50%
• Replication-competent 50%

Immunology and Microbiology

• Cytotoxic T-Cell 100%
• Immunogenicity 100%
• Vaccinia Virus 100%
• Immunotherapy 50%
• interferon 50%
• Innate Immune System 50%
• Inflammation Response 50%
• Viral Replication 50%
• Viral Vector 50%
• Adenoviridae 50%
• Cancer Antibody 50%
• Syngenic 50%
• Flank 50%
• Antineoplastic Activity 50%
• Oncolytic Virus 50%
• Activation of Immune Response 50%
• Vaccinium 50%
• Immune System 50%
• Replication 50%

Biochemistry, Genetics and Molecular Biology

• T Cell 100%
• CD8 100%
• Immunogenicity 100%
• Vaccinia Virus 100%
• Innate Immunity 50%
• Immune Response 50%
• Virus Replication 50%
• Virus Vector 50%
• Syngenic 50%
• Antineoplastic Activity 50%
• Adenoviridae 50%
• Vaccinium 50%
• Interferon 50%