Tumor-associated antigen peptides as anti-metastatic vaccines

Lea Eisenbach*, Ofer Mandelboim, Erez Bar-Haim, Lior Carmon, Hernan Copcow, Khaled El-Shami, Adrian Paz, Dan Popovic, Ezra Vadai, Esther Tzehoval, Michael Feldman, Mati Fridkin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Cytotoxic T-lymphocytes (CTLs) kill abnormal cells. CTLs recognize major histocompatibility complex class I molecules in complex with peptides derived from relevant antigens. The identification of tumor associated antigen peptides enabled the design of anti-tumor and anti-metastatic vaccines in a murine lung carcinoma.

Original languageEnglish
Pages (from-to)323-328
Number of pages6
JournalLetters in Peptide Science
Volume5
Issue number5-6
DOIs
StatePublished - 1998

Keywords

  • Immunotherapy
  • MHC class I
  • Tumor metastases

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