Tumor-associated antigen peptides as anti-metastatic vaccines

Lea Eisenbach; Ofer Mandelboim; Erez Bar-Haim; Lior Carmon; Hernan Copcow; Khaled El-Shami; Adrian Paz; Dan Popovic; Ezra Vadai; Esther Tzehoval; Michael Feldman; Mati Fridkin

doi:10.1007/BF02443479

Tumor-associated antigen peptides as anti-metastatic vaccines

Lea Eisenbach^*
, Ofer Mandelboim
, Erez Bar-Haim
, Lior Carmon
, Hernan Copcow
, Khaled El-Shami
, Adrian Paz
, Dan Popovic
, Ezra Vadai
, Esther Tzehoval
, Michael Feldman
, Mati Fridkin

^*Corresponding author for this work

Department of Immunology and Cancer Research

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Cytotoxic T-lymphocytes (CTLs) kill abnormal cells. CTLs recognize major histocompatibility complex class I molecules in complex with peptides derived from relevant antigens. The identification of tumor associated antigen peptides enabled the design of anti-tumor and anti-metastatic vaccines in a murine lung carcinoma.

Original language	English
Pages (from-to)	323-328
Number of pages	6
Journal	International Journal of Peptide Research and Therapeutics
Volume	5
Issue number	5-6
DOIs	https://doi.org/10.1007/BF02443479
State	Published - 1998

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Immunotherapy
MHC class I
Tumor metastases

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10.1007/BF02443479

Cite this

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abstract = "Cytotoxic T-lymphocytes (CTLs) kill abnormal cells. CTLs recognize major histocompatibility complex class I molecules in complex with peptides derived from relevant antigens. The identification of tumor associated antigen peptides enabled the design of anti-tumor and anti-metastatic vaccines in a murine lung carcinoma.",

keywords = "Immunotherapy, MHC class I, Tumor metastases",

author = "Lea Eisenbach and Ofer Mandelboim and Erez Bar-Haim and Lior Carmon and Hernan Copcow and Khaled El-Shami and Adrian Paz and Dan Popovic and Ezra Vadai and Esther Tzehoval and Michael Feldman and Mati Fridkin",

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AU - Eisenbach, Lea

AU - Mandelboim, Ofer

AU - Bar-Haim, Erez

AU - Carmon, Lior

AU - Copcow, Hernan

AU - El-Shami, Khaled

AU - Paz, Adrian

AU - Popovic, Dan

AU - Vadai, Ezra

AU - Tzehoval, Esther

AU - Feldman, Michael

AU - Fridkin, Mati

PY - 1998

Y1 - 1998

N2 - Cytotoxic T-lymphocytes (CTLs) kill abnormal cells. CTLs recognize major histocompatibility complex class I molecules in complex with peptides derived from relevant antigens. The identification of tumor associated antigen peptides enabled the design of anti-tumor and anti-metastatic vaccines in a murine lung carcinoma.

AB - Cytotoxic T-lymphocytes (CTLs) kill abnormal cells. CTLs recognize major histocompatibility complex class I molecules in complex with peptides derived from relevant antigens. The identification of tumor associated antigen peptides enabled the design of anti-tumor and anti-metastatic vaccines in a murine lung carcinoma.

KW - Immunotherapy

KW - MHC class I

KW - Tumor metastases

U2 - 10.1007/BF02443479

DO - 10.1007/BF02443479

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AN - SCOPUS:54749083500

SN - 1573-3149

VL - 5

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JO - International Journal of Peptide Research and Therapeutics

JF - International Journal of Peptide Research and Therapeutics

IS - 5-6

ER -

Tumor-associated antigen peptides as anti-metastatic vaccines

Abstract

UN SDGs

Keywords

Access to Document

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